Evaluation of brainstem auditory evoked potentials and their relationshipwith levels of thyroid autoantibodies in patients with vitiligo.

نویسندگان

  • İlhan Çeçen
  • Ayşe Serap Karadağ
  • Temel Tombul
  • Serap Güneş Bilgili
  • Ömer Çalka
  • Ahmet Zübeyir Burakgazi
چکیده

BACKGROUND/AIM Vitiligo is a common depigmenting disorder. The damage can also occur in similar ways to melanocytes within other organs. We evaluated the brainstem and auditory pathway functions by evaluating brainstem auditory evoked potentials (BAEPs) and whether there is any relationship between auditory functions and autoimmunity. MATERIALS AND METHODS Forty patients with vitiligo and 20 healthy volunteers were enrolled. Thyroid functions and autoantibodies were examined and BAEP tests were assessed by a neurologist. RESULTS Antithyroid peroxidase (anti-TPO) and antithyroglobulin (anti-TGA) antibody positivity was higher in the patient group (P < 0.05). A negative correlation was detected between anti-TPO and lead III, IV, and V latency and I-III interpeak latency (IPL) of the right ear together with lead IV latency and I-V IPL of the left ear in the patient group. When each BAEP parameter was compared between the two groups, more abnormalities were detected in the V latency and III-V IPL of the left ear together with IV and V latency of the right ear. CONCLUSION In this study the presence of a correlation between increased anti-TGA and anti-TPO levels and BAEP parameters may be related to an autoimmune-mediated mechanism. However, further studies are needed to be performed in a large patient series.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

معرفی شاخصه‌های سندرمی با کاهش شدید درک گفتار نامتناسب با آستانه شنوایی

Background: The objective of this study was to describe the audiologic and related characteristics of a group patient with speech perception affected out of proportion to pure tone hearing loss. A case series of patient were referred for evaluation and management to the Hearing Research Center.To describe the clinical picture of the patients with the key clinical feature of hearing loss for pur...

متن کامل

Auditory Brainstem Response Wave Amplitude Characteristics as a Diagnostic Tool in Children with Speech Delay with Unknown Causes

Speech delay with an unknown cause is a problem among children. This diagnosis is the last differential diagnosis after observing normal findings in routine hearing tests. The present study was undertaken to determine whether auditory brainstem responses to click stimuli are different between normally developing children and children suffering from delayed speech with unknown causes. In this cr...

متن کامل

Evaluation of Thyroid Autoantibodies in Type 2 Diabetes

OBJECTIVE: Diabetes mellitus and thyroid disease are the two common endocrinopathies seen in adult population. Studies to evaluate thyroid disorders in patients with type 2 diabetes are lacking. The aim of this study was to compare prevalence of thyroid dysfunction and autoim-munity in type 2 diabetic patients with age and sex matched non-diabetic control group. MATERIAL AND METHODS: Among pat...

متن کامل

Auditory processing skills in brainstem level of autistic children: A Review Study

Aims: Autism is a pervasive developmental disorder. Deficit in sensory functions is one of the characteristics of people with autism, and usually these people show abnormality in processing and correct interpretation of auditory information. Also people with Autism show problems in communicating with others. This review article deals with the accurate understanding of Auditory processing skills...

متن کامل

Objective Peak-Detection in Complex Auditory Brainstem Response to /ba/, /da/, /ga/: A Novel Technique

Objectives: The result of auditory brainstem response is used worldwide for detecting hearing impairments or hearing aids. This study aimed to introduce the superiority of mathematical innovation algorithm toward subjective evaluation by an audiologist. The automatic algorithm method is encouraged for detecting the waves of Auditory Brainstem Response (ABR), because it can reduce subjective eva...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Turkish journal of medical sciences

دوره 46 4  شماره 

صفحات  -

تاریخ انتشار 2016